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Interference with withdrawal signs of naloxone-induced opiate withdrawal under anesthesia is anesthetic-specific in opiate-dependent rats.

机译：在麻醉鸦片依赖的大鼠中，麻醉对纳洛酮诱发的鸦片鸦片撤药的干扰迹象是麻醉剂特异性的。

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摘要

We hypothesized that interference of opiate antagonist-precipitated withdrawal signs under anesthesia is anesthetic-specific. Three groups of morphine-dependent rats were compared in different experimental conditions using a protocol of rapid withdrawal induction by an antagonist under anesthesia. We observed that ketamine and midazolam have different effects on the expression of withdrawal. This brings specific insights into the pharmacological basis of therapy with induction of opiate antagonist.

机译：我们假设麻醉下阿片拮抗剂沉淀的戒断症状的干预是麻醉特异性的。在麻醉条件下，使用拮抗剂快速诱导退缩，在不同的实验条件下比较了三组吗啡依赖性大鼠。我们观察到氯胺酮和咪达唑仑对戒断的表达有不同的影响。这为鸦片拮抗剂的诱导治疗的药理基础带来了特殊见解。

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作者
Streel, Emmanuel; Dan, Bernard; Bredas, Philippe; Clement, B; Pelc, Isidore; Verbanck, Paul;
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年度 2001
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原文格式 PDF
正文语种 en
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1. Interference with withdrawal signs of naloxone-induced opiate withdrawal under anesthesia is anesthetic-specific in opiate-dependent rats. [J] . Streel E, Dan B, Bredas P, Life sciences . 2001,第5期

机译：在麻醉鸦片依赖的大鼠中，麻醉对纳洛酮诱导的鸦片撤药的撤药迹象的干预是麻醉剂特异性的。
2. Effects of anaesthetic agents in interference of naloxone-induced opiate-withdrawal are dose-dependent in opiate-dependent rats [J] . Streel E, Dan B, Antoniali V, Life sciences . 2005,第6期

机译：麻醉剂对纳洛酮诱导的阿片戒断的干预作用与剂量有关，在阿片依赖性大鼠中
3. Elevated mu-opioid receptor expression in the nucleus of the solitary tract accompanies attenuated withdrawal signs after chronic low dose naltrexone in opiate-dependent rats. [J] . Van Bockstaele EJ, Rudoy C, Mannelli P, Journal of Neuroscience Research . 2006,第3期

机译：鸦片依赖性大鼠中慢性低剂量纳曲酮注射后，孤立道核中的阿片类受体表达升高，同时伴有戒断症状减弱。
4. Application of MM waves in the therapy of withdrawal syndrome for opiate-dependent patients [C] . Glazyrina, N.I., Abolonin, . 2003

机译：MM波在阿片依赖患者戒断综合征治疗中的应用
5. Discrimination of an antagonist-precipitated withdrawal from an acute state of opiate dependence in rats. [D] . Jones, Nicholas Tyson. 2005

机译：在大鼠中从鸦片依赖的急性状态中识别出拮抗剂导致的戒断。
6. Glucocorticoid receptors participate in the opiate withdrawal-induced stimulation of rats NTS noradrenergic activity and in the somatic signs of morphine withdrawal [O] . Javier Navarro-Zaragoza, Juana M Hidalgo, M Luisa Laorden, 2012

机译：糖皮质激素受体参与阿片戒断所致大鼠NTS去甲肾上腺素能活性的刺激以及吗啡戒断的体征
7. A pharmacological modulation of opiate withdrawal using an up-/down-regulation of the noradrenergic system in opiate-dependent rats. [O] . Streel, Emmanuel, Dan, Bernard, Campanella, Salvatore, 2006

机译：在上阿片依赖性大鼠中使用去甲肾上腺素能系统的上/下调节来调节阿片戒断的药理作用。
8. Effects of Nicotine Withdrawal in Adult Male and Female Rats. [R] . Hamilton, K. R. 2008

机译：尼古丁戒断对成年雄性和雌性大鼠的影响。

Interference with withdrawal signs of naloxone-induced opiate withdrawal under anesthesia is anesthetic-specific in opiate-dependent rats.

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